EMBO | EMBL Symposia
EMBL Heidelberg, Germany, 19 - 22 May 2012 New Perspectives on Immunity to Infection
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Conference Shuttle Bus schedule available
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Abstract submission no longer possible
Why You Should Attend
Despite decades of study, the mechanisms determining host vulnerability versus resistance to pathogens remain poorly defined. This has impeded the rational design of vaccines and other forms of immunologic intervention.
This symposium will discuss new developments and approaches for overcoming critical gaps in our understanding of the pathogenesis of infectious diseases and immunity to infection.
Experts will discuss aspects of the host-pathogen interaction at the molecular, cellular, organism and population levels with the goal of identifying critical determinants that dictate whether this encounter leads to resistance or disease.
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Coming Next
EMBL Heidelberg, Germany, 13 - 16 September 2012 Diabetes and Obesity
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Registration is now open.
Why You Should Attend
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Summary
Over recent decades, the incidence of metabolic diseases such as obesity and diabetes has risen to epidemic proportions. Projections into the future suggest increasingly unmet patient needs and an unsustainable challenge for health care systems. Simultaneously, the drug discovery process is facing its own challenges. The number of pharmaceutical companies who are able to conduct expensive late stage clinical trials is declining. Funding for academic laboratories and biotechnology operations is limited. Novel strategies and new insights are needed to treat these diseases.
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Aims of event
This EMBO | EMBL Symposium aims to bring together established experts, physician scientists and basic researchers to discuss the multi-layered and complex processes leading up to novel therapeutic strategies for diabetes, obesity and related health issues, such as cancer and cardiovascular disease, including:- Mechanistic translational research addressing controversies of clinical relevance for diabetes and obesity
- Systems biology approaches dissecting multi-organ communication in the pathophysiology of metabolic disease
- Unraveling the emerging molecular interplays between immune processes and metabolic pathways
- Exploring novel insight into mechanisms of bariatric surgery and combination therapies for the development of future pharmacologics
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EMBL Heidelberg, Germany, 19 - 22 September 2012 Quality Control – From Molecules to Organelles
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Registration is now open - register here
The preliminary programme is now available here
Registration and payment deadline is Thursday 9 August 2012.
Abstract submission deadline is Thursday 12 July 2012.
Why You Should Attend
Research on quality control and stress response systems at the DNA, RNA and protein levels is experiencing explosive growth due to the realization of its importance in cell biology, ageing and major diseases.
Cells constantly suffer damage and make errors. This is the consequence of the intrinsic biochemical fragility of molecules and the limited robustness and precision of cellular processes. A multitude of internal and environmental stress insults aggravates this situation. All cells from bacteria to human have developed powerful quality control systems. These detect and minimize the damage that would ensue if mistakes and abnormal molecules went unchecked and uncorrected:
- Safeguarding systems which ensure proper performance of cellular processes or establish homeostatic environments, thereby avoiding errors and damage from occurring.
- Damage repair systems which detect damaged or abnormal macromolecules and repair or eliminate these.
- Stress response pathways that increase the cell's capacity to cope with specific or global stress.
This symposium addresses the molecular mechanisms of these systems, generating a unique forum of interdisciplinary discussion on quality control mechanisms of the genome (DNA), the transcriptome (RNA) and the proteome, and thus bringing together experts from traditionally separated fields.
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EMBL Heidelberg, Germany, 7 - 10 October 2012 The Complex Life of mRNA
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Registration is now open.
Registration and payment deadline is 23 August 2012. (Follow the left hand side menu: Registration and Payment.).
Abstract submission deadline is 2 August 2012.
The list of confirmed speakers is now available.
Before the genetic information stored in the DNA can be used to direct cell growth and metabolism it has to be transferred into RNA. Messenger RNAs (mRNAs) are key components in the transmission of genetic information in all life forms - from viruses to complex mammalian organisms. Exciting recent findings have revealed a remarkable degree of complexity in the lives of mRNAs and the field is rapidly developing.
The EMBO | EMBL Symposium “Complex Life of mRNA” will bring leaders in the mRNA field together with post-docs and students, with the aim of disseminating and discussing the most recent results. The programme includes sessions on:
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transcription;
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mRNA processing;
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export and localization;
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mRNA surveillance and decay;
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translation and the control of mRNA expression by microRNAs.
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EMBL Heidelberg, Germany, 13 - 16 October 2012 Germline - Immortality through Totipotency
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Registration is now open
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Speaker List Confirmed
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Poster available to download
Why You Should Attend
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Summary
What does immortality mean at the molecular, cellular, transgenerational and evolutionary level?Most organisms have a defined lifespan, however life of a species continues and evolves via germline from generation to generation. Recent studies show that tissue stem cells share molecular and developmental signatures with the germline and that even fully differentiated, postmitotic cells can be reprogrammed to regain totipotency.
This EMBO | EMBL Symposium will go beyond a description of the phenomena involving stem cell behaviour, programming and reprogramming. It will bring together researchers from different disciplines, who will address fundamental questions of totipotency as they relate to evolution, development and tissue specialization.
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Questions to be discussed include:
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how a need for germline specification arose during the evolution of multicellularity from single cells to colonies with specialized cell types;
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how the fertilized egg cell loses totipotency during formation of a multicelluar organism;
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how chromatin-based mechanisms influence totipotency both at the cellular and transgenerational level; and
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how the decision toward meiosis is achieved and regulated.
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Topics
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From single cells to multicellularity
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Keeping it all together: chromosomes and chromatin
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Programming and reprogramming
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Conservative vs progressive divisions (mitosis and meiosis)
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Context matters
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EMBL Heidelberg, Germany, 1 - 4 May 2013 New model systems for linking evolution and ecology
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Why you should attend
A major obstacle in linking evolution and ecology has been that for many of the preferred models for genetic and genomic research, ecological information has been lacking. Conversely, the preferred models for evolutionary ecology have generally not been amenable to genetic experiments and have had poorly developed genomic resources. The ongoing revolution in sequencing technologies is rapidly changing this. Large-scale sequencing-based studies have become affordable for individual labs and support population genomics, investigation of regulatory landscapes of the genomes as well as in situ genetics in a wide range of species. Importantly, such analyses can now be performed with hundreds or even thousands of individuals.
This meeting will present the latest advances with satellite systems, that is, species that are closely related to conventional genetic model organisms, and with entirely new models for evolutionary and ecological genetics and genomics. Special emphasis will be placed on the interaction between organisms as a basis for understanding ecological adaptation. If you want to bring a new species into the genomic era, this meeting is for you.
The programme includes sessions on
Microbe, plant and animal satellite species
Emerging model systems
Interactions and ecosystems
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EMBL Heidelberg, Germany, 3 - 6 October 2013 Seeing is Believing – Imaging the Processes of Life
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The processes of life are naturally dynamic in space and time from the molecular to the organismal level. The rapid development of imaging methods across this full scale of biological organization has revolutionized our ability to directly visualize the inner workings of proteins, protein complexes, organelles, cells, tissues, organs and whole organisms.
With the Symposium “Seeing is Believing – Imaging the Processes of Life” we aim to bring together the leading developers of imaging methods with cutting edge applications that illustrate how imaging can answer biological questions. We will place emphasis on methods that are able to capture the dynamics of life and aim to span the whole range from molecular resolution to imaging of whole organisms
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Past events
EMBL Advanced Training Centre, Heidelberg, Germany, 13 - 16 October 2011 Structure and Dynamics of Protein Networks
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Registration is no longer possible for this meeting.
The general aim of the symposium is to explore the possible synergisms and cross-talk between the large-scale and classical approaches to biological networks.
Understanding the molecular mechanisms of biological function largely relies on the systematic charting of the dynamics interactions taking place between the various components of living cells. Recent “OMICS” technologies contribute large biological networks covering entire proteomes. These networks are generally static as they fail to capture spatial and temporal dimensions that represent essential properties of living systems. Mechanistic and dynamic insights often come from focused smaller-scale approaches, such as those used in structural biology, biophysics or cell biology.
This symposium brings together leading scientists from the “OMICS” field with leading structural and cell biologists to discuss scientific issues arising at the interface of these complementary fields. Possible avenues to populate current networks with dynamics and mechanistic insights that will ensure high levels of biological understanding and contribute to deciphering fundamental principles will be reviewed and investigated.
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EMBL Advanced Training Centre, Heidelberg, Germany, 17 - 19 September 2011 Cancer Genomics
This symposium will provide an opportunity to learn about the rapidly progressing area of cancer genomics. It will incorporate presentations representing many of the major international cancer genome sequencing projects, as well as covering the areas of cancer epigenomics, mouse cancer models and the developments in both computational and bioinformatics fields that are required to manage, interpret and present these substantial datasets. The meeting will bring together scientists from across these areas for a unique opportunity to interact and stimulate further integration of these efforts.
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EMBL Advanced Training Centre, Heidelberg, Germany, 17 - 20 March 2011 Seeing is Believing – Imaging the Processes of Life
The processes of life are naturally dynamic in space and time from the molecular to the organismal level. The rapid development of imaging methods across this full scale of biological organization has revolutionized our ability to directly visualize the inner workings of proteins, protein complexes, organelles, cells, tissues, organs and whole organisms and ecosystems.
With the Symposium “Seeing is Believing – Imaging the Processes of Life” we aim to bring together the leading developers of imaging methods with cutting edge applications that illustrate how imaging can answer biological questions. We will place emphasis on methods that are able to capture the dynamics of life and aim to span the whole range from molecular resolution to imaging of whole organisms.
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EMBL Advanced Training Centre, Heidelberg, Germany, 13 - 16 October 2010 The Non-Coding Genome
This symposium will provide an interdisciplinary discussion of the roles of non-coding RNAs with the aim of enhancing our understanding of gene regulation and function. Topics will include recent discoveries in the fields of prokaryotic and eukaryotic long and short non-coding RNAs. The functional roles of non-coding RNAs in a wide variety of cell processes will be discussed.
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EMBL Advanced Training Centre, Heidelberg, Germany, 5 - 8 September 2010 Structure and Function of Neural Circuits
Understanding the complexity and functional composition of cellular and synaptic networks in the nervous system is a major challenge in neurobiology. Genes and molecules impact directly the assembly, function, and plasticity of specific neural circuits, and recent studies in different model systems start to elucidate the functionality of neuronal connectomes as an higher organisational entity required for the generation of complex behaviours.
The goal of this Symposium is to highlight recent work on the anatomical and functional analysis of behaviourally-relevant neural circuits in genetically tractable model systems, and to promote the exchange of ideas and methods in this exciting field of research.
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EMBL Advanced Training Centre, Heidelberg, Germany, 20 - 23 June 2010 Human Variation: Cause and Consequence
The goal of this Symposium is to explore human genetic and phenotypic variability in the light of recent developments in genomics, genetics and molecular medicine. The topics covered will include the mechanisms of mutation, normal sequence variation from the DNA to the chromosomal level, functional polymorphism and disease genetics.
Keynote Lectures will be delivered by Svante Pääbo, Max Planck Institute for Evolutionary Anthropology, and Kári Stefánsson, deCODE genetics.
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