Structure and Dynamics of Protein Networks
A. Gavin, M. Kaksonen, G. Superti-Furga
EMBL Advanced Training Centre, Heidelberg, Germany
Thursday 13 October - Sunday 16 October 2011

Programme
Sessions:
- Signalling Networks and Circuits – Information networks
- Structure-Based Networks
- Multiscale analysis and integration of Cellular Networks
- From Quantitative Network to Cell Biology – Cell Biology of Protein Networks
Welcome
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Day 1: Thursday 13 October 2011 |
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15:00 - 17:00 |
Arrival & Registration |
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17:15 - 17:30 |
Welcome |
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17:30 - 18:30 |
Keynote Session Peter E. Wright, The Scripps Research Institute - "Promiscuous liaisons: functional interactions of intrinsically disordered proteins in signaling networks" |
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18:30 - 20:00 |
Session 1 - Signalling Networks and Circuits – Information networks 18:30 - 19:00 Garry Nolan, Stanford School of Medicine - "Systems immunology at the single cell level" 19:00 - 19:30 Suzanne Gaudet, Harvard Medical School - "Life in the balance: variability in cellular responses to death-inducing ligands" |
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19:30 - 21:30 |
Dinner |
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21:00 - 23:00 |
Roof Top Lounge |
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Day 2: Friday 14 October 2011 |
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09:00 - 10:15 |
Session 1 (cont) - Signalling Networks and Circuits – Information networks 09:00 - 09:30 Giulio Superti-Furga, Center for Molecular Medicine of the Austrian Academy of Sciences - to follow 09:30 - 10:00 Marko Kaksonen, EMBL - "Dynamics of clathrin-mediated endocytosi in yeast" 10:00 - 10:15 Kenji Maeda, EMBL - "A map of non-vesicular lipid transport in Saccharomyces cerevisiae uncovered using tandem affinity purification-tag strains" |
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10:15 - 10:45 |
Coffee Break |
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10:45 - 11:45 |
Session 1 (cont) - Signalling Networks and Circuits – Information networks 10:45 - 11:15 Anne-Claude Gavin, EMBL - "A systematic screen for protein–lipid interactions in Saccharomyces cerevisiae" 11:15 - 11:30 Angelika Harbauer, Freiburg University -"Mitochondrial protein biogenesis is regulated by cytosolic kinases" 11:30 - 11:45 Evangelia Petsalaki, SLRI, Mount Sinai Hospital - "Systematic study of the role of human RhoGAPs/GEFs in the spatio-temporal control of Rho signaling specificity" |
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11:45 - 14:00 |
Lunch |
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14:00 - 15:45 |
Session 2 - Structure-Based Networks 14:00 - 14:30 Patrick Aloy, Institute for Research in Biomedicine - "A network medicine approach to human disease" 14:30 - 15:00 Martin Beck, EMBL - "Investigating human nuclear pore composition by targeted proteomics" 15:00 - 15:15 Guido Capitani, Paul Scherrer Institute - "An evolutionary method for distinguishing biological interfaces from crystal contacts: applications to structure-based networks" |
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15:15 - 15:45 |
Coffee Break |
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15:45 - 17:30 |
Session 2 - Structure-Based Networks 15:45 - 16:15 Tanja Kortemme, University of California, San Francisco - "Design and engineering of Proteins, interactions and networks" 16:15 - 16:45 Eva Wolf, MPI of Biochemistry - "Actions and interactions of circadian clock proteins" 16:45 - 17:15 Philip Selenko -Leibniz Institute of Molecular Pharmacology (FMP Berlin)"Cellular PTMs and Conformational Plasticity of Protein Network Hubs" 17:15 - 17:30 Guillermo Montoya, CNIO - "Crystal structure of the open conformation of the mammalian chaperonin CCT in complex with tubulin" |
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17:30 - 19:30 |
Poster Session 1 (Helix A) |
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19:30 - 21:00 |
Dinner |
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20:30 - 23:00 |
Roof Top Lounge |
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Day 3: Saturday 15 October 2011 |
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09:00 - 14:45 |
Session 3 - From Quantitative Network to Cell Biology – Cell Biology of Protein Networks 09:00 - 09:30 Ian Cheeseman, Whitehead Institute and Department of Biology, MIT - "Anatomy of a kinetochore: Building a microtubule attachment site" 09:30 - 10:00 François Nédélec, EMBL - "Effective spatial organization from simple cytoskeletal elements" 10:00 - 10:15Victor Sourjik, University of Heidelberg - "Robust information processing in bacterial chemotaxis" |
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10:15 - 10:45 |
Coffee Break |
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10:45 - 12:00 |
Session 3 (cont) - From Quantitative Network to Cell Biology – Cell Biology of Protein Networks 10:45 - 11:15 Marino Zerial, MPI of Molecular Cell Biology and Genetics - "Systems analysis of endosomal transport and signalling" 11:15 - 11:45 Jussi Taipale, University of Helsinki - to follow 11:45 - 12:00 Alejandro Granados, Universidad Nacional Autónoma de México - "Information processing in the signaling network of B. subtilis" |
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12:00 - 14:00 |
Lunch |
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14:00 - 14:45 |
Session 3 - From Quantitative Network to Cell Biology – Cell Biology of Protein Networks 14:00 - 14:30 Lucas Pelkmans, University of Zurich - "Functional and molecular diversification of the endocytic pathways and their cell-to-cell variability" 14:30 - 14:45 Markku Varjosalo, ETH Zurich - "Charting the human kinome interactome" |
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14:45 - 15:15 |
Coffee Break |
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15:15 - 16:15 |
Keynote Session Tom Kirchhausen, Harvard Medical School - "Dynamics of endocytosis " |
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16:15 - 17:15 |
Keynote Session Tony Pawson, Samuel Lunenfeld Research Institute Mt. Sinai Hospital - "Post-translational modifications in the assembly of regulatory protein networks" |
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17:15 - 19:15 |
Poster Session 2 |
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19:15 - 00:00 |
Dinner & Party |
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Day 4: Sunday 16 October 2011 |
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09:00 - 12:30 |
Session 4 - Multiscale analysis and integration of Cellular Networks 09:00 - 09:30 Chris Bakal, The Institute of Cancer Research - "Information Processing During Cellular Morphogenesis" 09:30 - 10:00 John Briggs, EMBL - "Studying dynamic membrane budding processes by correlating light and electron microscopy" 10:00 - 10:30 Natasa Przulj, Imperial College London - "Network topology complements sequence as a source of biological information" |
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10:30 - 11:00 |
Coffee Break |
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11:00 - 12:30 |
Session 4 (cont) - Multiscale analysis and integration of Cellular Networks 11:00 - 11:30 Ben Lehner, CRG Centre for Genomic Regulation - "Dynamics of genetic interaction networks" 11:30 - 12:00 Aurelien Roux, University of Geneva - "Essential elastic and shape parameters govern the dynamics and energetics of dynamin-mediated membrane fission" 12:00 - 12:15 Oleksiy Kovtun, Institute for Molecular Bioscience - "All in vitro approach to deciphering assembly of multisubunit protein complexes" 12:15- 12:30 Zoe Hilioti, Centre for Research and Technology Hellas (CERTH) - "Mapping of signaling events during collective life formation" |
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12:30 - 12:45 |
Closing Remarks |