Quality Control – From Molecules to Organelles

B. Bukau, J. Diffley, M. Hentze

EMBL Heidelberg, Germany

Wednesday 19 September - Saturday 22 September 2012

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Preliminary Programme

 

Day 1 - Wednesday 19 September 2012

15:00 - 17:00

Arrival & Registration

17:00 - 17:30

Welcome and Opening Remarks

17:30 - 20:00

Keynote Lectures

Elisa Izaurralde, Max Planck Institute for Developmental Biology, Germany - "Quality Control of Eukaryotic mRNA"

Stefan Jentsch, Max Planck Institute of Biochemistry, Germany - "DNA Double-Strand Break Repair: Mechanisms and Regulation"

Jonathan Weissman, University of California, USA - "Quality Control in the Endoplasmic Reticulum"

20:00 - 23:00

Dinner, followed by drinks in the ATC Roof Top Lounge until 23:00

 

 

Day 2 - Thursday 20 September 2012

09:00 - 12:00

Session 1: Quality control of genomic information

Tony Carr, CanceGenome Damage and Stability Centre, University of Sussex, United Kingdom - "Error Prone Replication Restart Following Fork Collapse"

Andrea Musacchio, Max-Planck Institute of Molecular Physiology, Germany - "Homeostatic Control of Cell Division"

Angelika B. Amon, Koch Institute for Integrative Cancer Research, HHMI, MIT, USA - "Effects of Aneuploidy on Protein Homeostasis"

Thomas Sommer, MDC Berlin, Germany - "Preliminary title to be announced"

Don W. Cleveland, Ludwig Institute for Cancer Research, USA -"Guarding the genome, the mitotic checkpoint, aneuploidy and tumorigenesis "

Short talks will be selected from abstracts

12:00 - 14:00

Lunch

14:00 - 18:00

Session 2: Quality control of transcription and RNA

Andrés Aguilera, Andalusian Molecular Biology and Regenerative Medicine Centre, Spain - "Transcription-dependent and -independent Mechanisms of Recombination-mediated Genome Instability"

Elena Conti, Max Planck Institute of Biochemistry, Germany - "The nonsense-mediated mRNA decay quality control pathway"

Patrick Cramer, University of Munich, Germany - "Mechanisms of mRNA Transcription Fidelity and Proofreading"

Andreas Kulozik, University of Heidelberg, Germany - "Stress Induced Regulation of 3' end mRNA Processing"

Jesper Svejstrup, Cancer Research UK, United Kingdom - "Quality Control During Transcription"

Short talks will be selected from abstracts

18:00 - 20:00

Poster Session 1

20:00 - 23:00

Dinner, followed by drinks in the ATC Roof Top Lounge until 23:00

 

 

Day 3 - Friday 21 September 2012

09:00 - 12:00

Session 3: Quality control of RNA and protein biogenesis

Paul Anderson, Harvard University, USA - "How tRNA Inhibits Protein Synthesis During Stress"

Rachel Green, Johns Hopkins University School of Medicine, USA - "Preliminary title to be announced"

Cecília M. Arraiano, ITQB-Universidade Nova de Lisboa, Portugal - "Preliminary title to be announced"

Anne Bertolotti, MRC Laboratory of Molecular Biology, United Kingdom - "Protein misfolding stress and translational control"

Short talks will be selected from abstracts

12:00 - 14:00

Lunch

14:00 - 18:00

Session 4: Quality control of Proteins

Judith Frydman, Stanford University, USA - "Protein folding and Quality Control in the Eukaryotic Cytosol"

Ulrich Hartl, Max-Planck-Institut of Biochemistry, Germany - "Chaperone Mechanisms in Protein Folding and Proteostasis"

Rick Morimoto, Northwestern University, USA - "Protein Homeostasis - Regulating the Stability of the Protein in Aging and Disease"

Kaz Nagata, Kyoto Sangyo University, Japan - "ER Homeostasis"

Lea Sistonen, Åbo Akademi University, Finland - "Stress-Inducible Post-Translational Modifications Regulating the Activity and Expression of Heat Shock Factors"

Short talks will be selected from abstracts

18:00 - 20:00

Poster Session 2

20:00 - 00:00

Gala Dinner

 

 

Day 4 - Saturday 24 September 2012

09:00 - 11:00

Session 5: Quality control of organelles and organisms

Andy Dillin, Salk Institute, USA - "Programming Proteostasis from a Distance; Metazoan Control of Protein Quality Control"

Jennifer Lippincott-Schwartz, NICHD, USA - "Preliminary title to be announced"

Short talks will be selected from abstracts

11:00 - 13:00

Session 5: Degradation pathways & Ubiquitin

Ivan Dikic, Goethe University, Frankfurt, Germany - "Ubiquitin Signaling in Quality Control"

Michael Rape, University of California, USA - "Novel Roles for Ubiquitin in Controlling Cell Division"

Short talks will be selected from abstracts

13:00 - 13:30

Closing remarks and lunch