Germline - Immortality through Totipotency
R. Lehmann, E. Heard, J. Rossant
EMBL Heidelberg, Germany
Saturday 13 October - Tuesday 16 October 2012
Final Programme
| 15:00 - 17:20 | Arrival & Registration |
|---|---|
| 17:20 - 17:30 | Welcome and Opening Session Chair: Ruth Lehmann |
| 17:30 - 18:20 |
Keynote Lecture: Induction of pluripotency by the female germline
John Gurdon, Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, United Kingdom |
| 18:20 - 18:45 |
Establishing pluripotency in the blastocyst Janet Rossant, University of Toronto, Canada |
| 18:45 - 19:10 |
Developmental Dynamics of X-Chromosome Inactivation in Mammals Edith Heard, Institut Curie, France |
| 19:10 - 19:25 |
Selected Short Talk 1 Molecular determinants of histone retention in mouse and human spermatozoa Antoine HFM Peters, Friedrich Miescher Institute for Biomedical Research (FMI), Switzerland |
| 19:30 - 20:30 | Dinner |
| 20:30 - 22:30 | After Dinner Drinks |
| Session 1: From Single Cell to Multicellularity Chair: Edith Heard |
|
| 09:00 - 09:25 |
Symmetry breaking in mouse development
Takashi Hiiragi, EMBL, Germany |
| 09:25 - 09:50 |
Epigenetic mechanisms of cell potency
Maria-Elena Torres-Padilla, The Institute of Genetics and Molecular and Cellular Biology, France |
| 09:50 - 10:05 |
Selected Short Talk 2 Early lineage specification in a marsupial Stephen Frankenberg, University of Melbourne, Australia |
| 10:05 - 10:30 |
Visualizing the mechanisms of spindle assembly and homologous chromosome segregation in mammalian oocytes Jan Ellenberg, EMBL, Germany |
| 10:30 - 11:00 | Morning Coffee Break |
| 11:00 - 11:25 |
Chromosome segregation in oocytes Kim Nasmyth, University of Oxford, United Kingdom |
| 11:25 - 11:40 |
Selected Short Talk 3 Protein aggregate fusion facilitates a switch between immortality and ageing Miguel C Coelho, MPI-CBG, Germany |
| 11:40 - 12:30 |
Keynote Lecture
Programming germ cells for totipotency and early mammalian development Azim Surani, Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, United Kingdom |
| 12:30 - 14:00 | Lunch |
| Session 2: Chromosomes and Chromatin Chair: Janet Rossant |
|
| 14:00 - 14:25 |
Chromatin Dynamics in Vertebrate Germlines
Bradley R. Cairns, University of Utah, USA |
| 14:25 - 14:50 |
C. elegans germ granules maintain germline fate and totipotency
Susan Strome, University of California Santa Cruz, USA |
| 14:50 - 15:15 |
The H3K27 demethylase Utx facilitates somatic and germ cell epigenetic reprogramming to pluripotency Jacob Hanna, Weizmann Institute of Science, Israel
|
| 15:15 - 15:30 |
Selected Short Talk 4
Tex19 paralogs, two new members of mammalian Piwi protein family Stephane Viville, IGBMC, France |
| 15:30 - 16:00 | Afternoon Coffee Break |
| 16:00 - 16:25 |
Epigenetic inheritance from the oocyte
Déborah Bourc’his, INSERM, France |
| 16:25 - 16:50 |
Systems Biology of Stem Cells Huck Hui NG, Genome Institute of Singapore, Singapore |
| 16:50 - 17:05 |
Selected Short Talk 5
DNA methylation establishment in mammalian oocytes is determined by transcription events Gavin Kelsey, The Babraham Institute, United Kingdom |
| 17:05 - 17:30 | Fast Track Poster Presentation Session |
| 17:30 - 19:30 | Poster Session |
| 19:30 - 20:30 | Dinner |
| 20:30 - 22:30 | After Dinner Drinks |
| Session 3: Programming and Reprogramming Chair: Bradley R. Cairns |
|
| 09:00 - 09:25 |
Mechanisms of reprogramming to pluripotency
Katrin Plath, University of California, Los Angeles, USA |
| 09:25 - 09:50 |
Epigenetic Reprogramming in Mammalian Development
Wolf Reik, Babraham Institute, United Kingdom |
| 09:50 - 10:05 |
Selected Short Talk 6
Direct conversion of germ cells into specific somatic cell types Baris Tursun, Max-Delbrück-Center, Germany |
| 10:05 - 10:30 |
The cellular and molecular basis for planarian regeneration Peter W. Reddien, Whitehead Institute, Massachusetts Institute of Technology, USA |
| 10:30 - 11:00 | Morning Coffee Break |
| 11:00 - 11:25 |
Protecting the Germline Ruth Lehmann, New York University School of Medicine and HHMI, USA |
| 11:25 - 11:40 |
Selected Short Talk 7
The co-chaperone Shutdown defines a group of biogenesis factors essential for all piRNA populations in Drosophila Daniel Olivieri, IMBA, Austria |
| 11:40 - 12:30 |
Control of germ cell commitment in yeast
Keynote Lecture: Angelika Amon, The Koch Institute, Massachusetts Institute of Technology, USA |
| 12:30 - 14:00 | Meet the Speaker Lunch |
| Session 4: Context Matters Chair: David C. Page |
|
| 14:00 - 14:25 |
Epigenetic regulation of aging
Anne Brunet, Stanford University, USA |
| 14:25 - 14:50 |
Asymmetric chromosome segregation during stem cell division in Drosophila male germline
Yukiko Yamashita, University of Michigan, USA . |
| 14:50 - 15:15 |
Mechanisms of position-dependent specification of cell fates in preimplantation embryos
Hiroshi Sasaki, Kumamoto University, Japan |
| 15:15 - 15:45 | Afternoon Coffee Break |
| 15:45 - 16:10 |
Germline function in mice and men
Marty M. Matzuk, Baylor College of Medicine, USA |
| 16:10 - 16:25 |
Selected Short Talk 7
Physiological control of niche and stem cell establishment Dana Gancz, Weizmann Institute of Science, Israel |
| 16:25 - 16:45 | Fast Track Poster Presentation Session |
| 16:45 - 18:30 | Poster Session |
| 18:30 till late | Conference Gala Dinner with live music |
| Session 5: Renewal vs Differentiation Chair: Susan Strome |
|
| 09:00 - 09:25 |
Mechanism and reconstitution in vitro of germ cell specification in mice Mitinori Saitou, Kyoto University, Japan |
| 09:25 - 09:50 |
Chromatin dynamics and early development Geneviève Almouzni, CNRS Institut Curie, France |
| 09:50 - 10:15 |
Determining germline fate in Arabidopsis ovules Ueli Grossniklaus, University of Zurich, Switzerland |
| 10:15 - 10:30 |
Selected Short Talk 9
Endogenous Nodal signaling regulates germ cell potency in the developing testis Peter Koopman, The University of Queensland, Australia |
| 10:30 - 11:00 | Morning Coffee Break |
| 11:00 - 11:25 |
Development in vivo of Fertilization-Competent Oocyte-like Cells in the Absence of Meiotic Initiation or Prophase
David C. Page, Whitehead Institute, Massachusetts Institute of Technology, USA |
| 11:25 - 11:50 |
Regulation of self-renewal and differentiation In germline stem cells
Rafal Ciosk, Friedrich Miescher Institute for Biomedical Research, Switzerland |
| 11:50 - 12:15 |
Genetic and Epigenetic studies of longevity: what are we learning about aging? Brian K. Kennedy, Buck Institute, USA |
| 12:15 - 12:20 | Symposium Ends |
| 12:30 - 13:00 | Packed Lunch |
| 12:45 | Buses Depart |