EMBO | EMBL Symposia 2012

EMBL Heidelberg, Germany, 19 - 22 May 2012 New Perspectives on Immunity to Infection

New Perspectives on Immunity to Infection

Latest News

New Keynote Speaker confirmed:  Professor Sir Andrew McMichael FRS, FMedSci,  Weatherall Institute of Molecular Medicine

Why You Should Attend

Despite decades of study, the mechanisms determining host vulnerability versus resistance to pathogens remain poorly defined. This has impeded the rational design of vaccines and other forms of immunologic intervention.

This symposium will discuss new developments and approaches for overcoming critical gaps in our understanding of the pathogenesis of infectious diseases and immunity to infection.

Experts will discuss aspects of the host-pathogen interaction at the molecular, cellular, organism and population levels with the goal of identifying critical determinants that dictate whether this encounter leads to resistance or disease.

 

 

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Coming Next

Diabetes and Obesity

EMBL Heidelberg, Germany, 13 - 16 September 2012 Diabetes and Obesity

Latest News

  • Registration is now open.

Why You Should Attend

  • Summary
    Over recent decades, the incidence of metabolic diseases such as obesity and diabetes has risen to epidemic proportions. Projections into the future suggest increasingly unmet patient needs and an unsustainable challenge for health care systems. Simultaneously, the drug discovery process is facing its own challenges. The number of pharmaceutical companies who are able to conduct expensive late stage clinical trials is declining. Funding for academic laboratories and biotechnology operations is limited. Novel strategies and new insights are needed to treat these diseases.

  • Aims of event
    This EMBO | EMBL Symposium aims to bring together established experts, physician scientists and basic researchers to discuss the multi-layered and complex processes leading up to novel therapeutic strategies for diabetes, obesity and related health issues, such as cancer and cardiovascular disease, including:

    • Mechanistic translational research addressing controversies of clinical relevance for diabetes and obesity
    • Systems biology approaches dissecting multi-organ communication in the pathophysiology of metabolic disease
    • Unraveling the emerging molecular interplays between immune processes and metabolic pathways
    • Exploring novel insight into mechanisms of bariatric surgery and combination therapies for the development of future pharmacologics

 

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Quality Control – From Molecules to Organelles

EMBL Heidelberg, Germany, 19 - 22 September 2012 Quality Control – From Molecules to Organelles

Latest News

Registration is now open - register here

The preliminary programme is now available here

Registration and payment deadline is Thursday 9 August 2012.

Abstract submission deadline is Thursday 12 July 2012.

 

Why You Should Attend

Research on quality control and stress response systems at the DNA, RNA and protein levels is experiencing explosive growth due to the realization of its importance in cell biology, ageing and major diseases.

Cells constantly suffer damage and make errors. This is the consequence of the intrinsic biochemical fragility of molecules and the limited robustness and precision of cellular processes. A multitude of internal and environmental stress insults aggravates this situation. All cells from bacteria to human have developed powerful quality control systems. These detect and minimize the damage that would ensue if mistakes and abnormal molecules went unchecked and uncorrected:

  • Safeguarding systems which ensure proper performance of cellular processes or establish homeostatic environments, thereby avoiding errors and damage from occurring.
  • Damage repair systems which detect damaged or abnormal macromolecules and repair or eliminate these.
  • Stress response pathways that increase the cell's capacity to cope with specific or global stress.

This symposium addresses the molecular mechanisms of these systems, generating a unique forum of interdisciplinary discussion on quality control mechanisms of the genome (DNA), the transcriptome (RNA) and the proteome, and thus bringing together experts from traditionally separated fields.

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The Complex Life of mRNA

EMBL Heidelberg, Germany, 7 - 10 October 2012 The Complex Life of mRNA

Latest news:

Registration is now open.

Registration and payment deadline is  23 August 2012. (Follow the left hand side menu: Registration and Payment.).

Abstract submission deadline is  2 August 2012.

The list of confirmed speakers is now available.

 

Before the genetic information stored in the DNA can be used to direct cell growth and metabolism it has to be transferred into RNA.  Messenger RNAs (mRNAs) are key components in the transmission of genetic information in all life forms - from viruses to complex mammalian organisms. Exciting recent findings have revealed a remarkable degree of complexity in the lives of mRNAs and the field is rapidly developing.

The EMBO | EMBL Symposium “Complex Life of mRNA” will bring leaders in the mRNA field together with post-docs and students, with the aim of disseminating and discussing the most recent results. The programme includes sessions on:

  • transcription;

  • mRNA processing;

  • export and localization;

  • mRNA surveillance and decay;

  • translation and the control of mRNA expression by microRNAs.

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Germline - Immortality through Totipotency

EMBL Heidelberg, Germany, 13 - 16 October 2012 Germline - Immortality through Totipotency

Latest News

  • Registration is now open

  • Speaker List Confirmed

  • Poster available to download

Why You Should Attend

  • Summary
    What does immortality mean at the molecular, cellular, transgenerational and evolutionary level?

    Most organisms have a defined lifespan, however life of a species continues and evolves via germline from generation to generation. Recent studies show that tissue stem cells share molecular and developmental signatures with the germline and that even fully differentiated, postmitotic cells can be reprogrammed to regain totipotency.

    This EMBO | EMBL Symposium will go beyond a description of the phenomena involving stem cell behaviour, programming and reprogramming. It will bring together researchers from different disciplines, who will address fundamental questions of totipotency as they relate to evolution, development and tissue specialization.

  • Questions to be discussed include:

    • how a need for germline specification arose during the evolution of multicellularity from single cells to colonies with specialized cell types;

    • how the fertilized egg cell loses totipotency during formation of a multicelluar organism;

    • how chromatin-based mechanisms influence totipotency both at the cellular and transgenerational level; and

    • how the decision toward meiosis is achieved and regulated.

  • Topics

    • From single cells to multicellularity

    • Keeping it all together: chromosomes and chromatin

    • Programming and reprogramming

    • Conservative vs progressive divisions (mitosis and meiosis)

    • Context matters

 

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