Location & dates EMBL Heidelberg, Germany 16 - 19 Sep 2015
Deadlines Registration closed Abstract submission closed

EMBL Courses and Conferences during the Coronavirus pandemic

With the onsite programme paused, many of our events are now being offered in virtual formats.

Registration is open as usual for many events, with back-up plans in place to move further courses and conferences online as necessary. Registration fees for any events affected by the COVID-19 disruption are fully refundable.

More information for participants of events at EMBL Heidelberg can be found here.

Final Programme

Day 1 - Wednesday 16 September
11:15-13:15 Registration and Lunch
13:15-13:30 Opening remarks

Session 1A: Impact of mobile DNA on genome structure and evolution
Chair: Duncan Odom

13:30-14:00 Impact of transposable elements on transcription regulation in human
Guillaume Bourque
, McGill University and Genome Québec Innovation Center, Canada
14:00-14:30 Structural variation and mobile element analysis in numerous of genomes
Jan Korbel, EMBL Heidelberg, Germany
14:30-14:45 Regulation of gene expression by proteins bound to LINE-derived RNA elements
Jan Attig, University College London (UCL), UK
14:45-15:00 An evolutionary arms race between KRAB zinc finger genes ZNF91/ZNF93 and SVA/L1 retrotransposons
Frank Jacobs, University of Amsterdam, The Netherlands
15:00-15:30 Retroposition and the origins and functional evolution of new mammalian genes
Henrik Kaessmann
, University of Lausanne, Switzerland
15:30-16:00 COFFEE BREAK and Meet the speakers session
16:00-16:30 Transposable elements drive E. coli adaptation to host environments?
Isabel Gordo
, IGC, Portugal 
16:30-16:45 Identifying regulatory modules in transposable elements and understanding their evolution
Vasavi Sundaram, Washington University School of Medicine, USA
16:45-17:00 Baboon Alus gone wild
Miriam Konkel, Louisiana State University, USA
17:00-17:15 Transposable elements and gene expression control in trypanosomatids
Adriana Ludwig, Instituto Carlos Chagas - ICC- FIocruz-PR, Brazil

Keynote Session I
Chair: Duncan Odom

17:15-18:15 Dynamic duplications and primate genome evolution
Evan Eichler
, University of Washington, USA
18:15-20:00 DINNER in the EMBL Canteen and Meet the speakers session

Welcome Reception in the ATC Roof Top Lounge

Day 2 - Thursday 17 September

Session 1B: Impact of mobile DNA on genome structure and evolution
Chair: Duncan Odom

09:00-09:30 Charting the epigenetic landscape of human transposable elements
Ting Wang
, Washington University in St. Louis School of Medicine, USA
09:30-10:00 Roles of human transposable elements in disease
Kathleen H. Burns, Johns Hopkins University School of Medicine, USA
10:00-10:15 L1-mediated retrotransposition and Alu/Alu homologous recombination driven germline chromothripsis
Lusine Nazaryan-Petersen, Wilhelm Johannsen Centre for Functional Genome Research, University of Copenhagen, Denmark
10:15-10:45 Transposable elements and the Dynamic Genome
Ellen Pritham
, The University of Utah, USA
10:45-11:15 COFFEE BREAK and Meet the speakers session

Keynote Talk Session II
Chair: Donal O’Carroll

11:15-12:15 Listening to the silence of transposons
Phillip Zamore
, University of Massachusetts Medical School, USA
12:15-14:00 LUNCH and Meet the speakers session

Session 2A: Transposon defense
Chair: Donal O’Carroll

14:00-14:30 Genome Defence in the Mammalian Germline
Ian Adams, MRC Institute of Genetics and Molecular Medicine at The University of Edinburgh, UK
14:30-14:45 Role of the mobile genome in cell identity, reprogramming and disease
Valerio Orlando, King Abdullah University of Science and Technology (KAUST), Saudi Arabia
14:45-15:00 Establishment of Chromatin Modification: How the Cell Recognizes and Triggers Transposable Elements for Transcriptional Silencing
Keith R. Slotkin, The Ohio State University, USA
15:00-15:15 Acute demethylation of IAP retrotransposons simulating in vivo epigenetic reprogramming reveals the involvement of small RNA pathways
Rebecca Berrens, The Babraham Institute, UK
15:15-15:45 Maelstrom vs. Retrotransposons in the mouse germline
Alex Bortvin
, Carnegie Institution for Science, USA
15:45-16:00 PIWI slicing and RNA elements in precursors instruct directional primary piRNA biogenesis
Radha Raman Pandey, CNRS-UJF-EMBL, France
16:00-16:30 COFFEE BREAK and Meet the speakers session
16:30-17:00 Evidence for co-evolution of nuclear pores and the piRNA transposon silencing system
William E. Theurkauf
, University of Massachusetts Medical School, USA
17:00-17:15 H2B methylation – a new guardian of transposable elements
Robert Schneider, IGBMC, France
17:15-17:30 An epigenetic switch ensures transposon repression upon acute loss of DNA methylation in ES cells
Marius Walter, Institut Curie / CNRS, France
17:30-17:45 Tex19.1, regulates LINE-1 ubiquitylation, protein stability and retrotransposition in the mammalian germline
Marta García-Cañadas, Centre for Genomics and Oncological Research (GENYO), Spain
17:45-18:15 Evolution of RNA based transposon defences
Eric A. Miska
, The Gurdon Institute, University of Cambridge, UK
18:15-18:30 Poster Flash Talks Session
Ariumi Yasuo, Kumamoto University, Japan
Patricia Carreira, Mater Research Institute-University of Queensland, Australia
Maria Placentino, Institute for Molecular Biology - IMB, Germany
Erika Kvikstad, University of Oxford, UK
Mofang Liu, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, China
Iñigo Narvaiza, The Salk Institute, USA
LeeAnn Ramsay, McGill University, Canada
18:30-20:00 POSTER SESSION I (Numbers 54-116, Helix A)
20:00-21:30 DINNER in the EMBL canteen and Meet the speakers session
21:30-23:00 Drinks in the ATC Roof Top Lounge
Day 3 - Friday 18 September

Session 2B: Transposon defense
Chair: Eric Miska

09:00-09:30 Endogenous retroviruses and the immune system of the host
George Kassiotis
, MRC National Institute for Medical Research, UK
09:30-10:00 Oxytricha: A symbiosis between mobile DNA and host genome rearrangement
Laura F. Landweber
, Princeton University, USA
10:00-10:15 The AC40 subunit of RNA polymerase III determines sites of Ty1 retrotransposon integration
Pascale Lesage, Inserm - CNRS - Université Paris Diderot, France
10:15-10:45 COFFEE BREAK and Meet the speakers session
10:45-11:15 The endovirome and its polydactyl controllers establish human-specific transcriptional networks
Didier Trono
, EPFL, Switzerland
11:15-11:30 The natural landscape and functional impact of transposon mobilization in Arabidopsis
Leandro Quadrana, IBENS, France
11:30-11:45 miR-34a deficiency in embryonic stem cells yields totipotent-like cell fate potential by inducing MERVL endogenous retroviruses
Lin He, University of California, Berkeley, USA
11:45-12:15 Transposons activation and epigenetic reprogramming: cause or consequence?
Maria Elena Torres Padilla
, IGBMC, CNRS, France
12:30-14:00 LUNCH and Meet the speakers session

Session 3: Mechanisms of Transposition
Chair: John Moran

14:00-14:30 Transferring drug-resistance with transposons: Structural insights into the mechanism of a conjugative transposon
Orsolya Barabas
, EMBL Heidelberg, Germany
14:30-14:50 Structural basis of mariner transposon integration: architecture of the Mos1 strand-transfer complex
Julia Richardson, University of Edinburgh, UK
14:50-15:15 Duncan Odom, University of Cambridge, Cancer Research UK-Cambridge Institute, UK
15:15-15:45 The telltales of transposition: What can we learn from target site duplications?
Fred Dyda
, NIDDK, National Institutes of Health, USA
15:45-16:00 Structure and mechanism of Ty3 retrotransposon reverse transcriptase
Marcin Nowotny, International Institute of Molecular and Cell Biology, Poland
16:00-16:30 COFFEE BREAK and Meet the speakers session
16:30-17:00 What keeps Mu transposition from going backwards?
Phoebe A. Rice
, The University of Chicago, USA 
17:00-17:15 Identification and Characterization of Host Proteins that Interact with the Human LINE-1 ORF2-encoded Protein
Tomoichiro Miyoshi, University of Michigan, USA
17:15-17:45 Structural characterisation of human non-LTR retrotransposons
Oliver Weichenrieder
, MPI for Developmental Biology, Germany

Keynote Talk Session III
Chair: John Moran

17:45-18:45 A potential role for somatic retrotransposition in oncogenesis
Haig Kazazian
, The Johns Hopkins University School of Medicine, USA
18:45-19:00 Poster Flash Talks Session
Gerald Schumann, Paul-Ehrlich-Institut, Germany
Kirsten Senti, Institute of Molecular Biotechnology Austria (IMBA), Austria
Manvendra Singh, Max-Delbruck Centre for Molecular Medicine, Germany
Priscilla Turelli, EPFL, Switzerland
Thomas Wicker, University of Zurich, Switzerland
Miguel Zaratiegui, Rutgers, the State University of New Jersey, USA
19:00-20:30 POSTER SESSION II (Numbers 117-180, Helix B)
20:30-24:00 Conference Dinner and Party and Meet the speakers session
Day 4 - Saturday 19 September
Session 4: Transposons in development and physiology
Chair: Orsolya Barabas

09:00-09:30 A 3’ poly(A) tract is required for LINE-1 retrotransposition
John Moran
, University of Michigan Medical School, USA
09:30-10:00 Domesticated piggyBac transposases and programmed DNA elimination in Paramecium
Mireille Bétermier
, CGM, CNRS, France
10:00-10:15 Fighting fire with fire: endogenous retroviruses coopted to regulate host innate immunity
Cedric Feschotte, University of Utah School of Medicine, USA
10:15-10:30 PIWI proteins in human neuronal development
Alberto Frangini, University of Cambridge, UK


COFFEE BREAK and Meet the speakers session
11:00-11:30 LINE activity in zebrafish development
Jose Luis García Pérez
, GENYO, Spain
11:30-11:45 Uhrf1/Np95 acts a key regulator of neural stem cell differentiation in vivo
Vidya Ramesh, Helmholtz Zentrum, Germany
11:45-12:00 Characterising somatic transposition events in the Drosophila brain
Christoph Treiber, CNCB - University of Oxford, UK
12:00-12:30 Neurogenic L1 retrotransposition: on the road to function
Geoffrey Faulkner
, Mater Medical Research Institute, Australia
12:30-12:45 Hitchhiking of coding and regulatory regions through the tumor genome by LINE-1
Jose Tubio, Wellcome Trust Sanger Insitute, UK
12:45-14:00 LUNCH in the EMBL Canteen and Meet the speakers session
14:00-14:30 Interspersed repeats: just junk or a key to chromosome biology
Jeanne B. Lawrence
, University of Massachusetts Medical School, USA

Keynote Session IV
Chair: Orsolya Barabas

14:30-15:30 Effects of endogenous retroviruses on normal and cancer transcriptomes
Dixie Mager
, Terry Fox Laboratory, Canada
15:30-15:45 Closing remarks

Post Conference Social Event:
German seasonal delight: Neuer Wein und Zwiebelkuchen

16:30 Bus to downtown and Frankfurt Airport