Location & dates EMBL Heidelberg, Germany 11 - 14 Oct 2015
Deadlines Registration closed Abstract submission closed

Final Programme

Day 1 - Sunday 11 October
12:00-14:00 Registration and Lunch
14:00-14:10 Opening remarks
14:10-15:00 Women in Science Session - Moderator: Carol Gross
15:00-15:30 COFFEE BREAK

Session 1: Bacterial Systems Biology
Chairs: Victor Sourjik & Pedro Beltrao

15:30-15:55 Using Systems Approaches to Study Pathogenesis: Bridging Networks and Mechanism
Nevan Krogan
, University of California, San Francisco, USA
15:55-16:10 Interactome profiling during infection reveals host cell signalling complexes induced by bacterial effectors
Gunnar Schroeder, Imperial College London, UK
16:10-16:35 Co translational membrane targeting, folding and assembly of proteins studied by selective ribosome profiling
Bernd Bukau
, ZMBH, Heidelberg University and DKFZ, Germany
16:35-16:50 Plasmaquellung und Wachstum: Comparative mechanics of bacterial cell growth
Enrique Rojas, Stanford University, USA
16:50-17:20 COFFEE BREAK
17:20-17:35 A Comprehensive, CRISPR based Approach to Functional Analysis of Essential Genes
Jason Peters, University of California, San Francisco, USA
17:35-18:00 Systematic approaches to interactome mapping
Anne-Claude Gavin
, EMBL Heidelberg, Germany
18:00-18:15 Cross species comparison of drug drug interactions
Ana Rita Brochado, EMBL Heidelberg, Germany
18:15-18:40 Network based interpretation of omics data
Kathleen Marchal, Ghent University, Belgium
18:40-18:55 Metagenome characterization using high throughput 3C data
Martial Marbouty, Institut Pasteur, France
19:00-20:30 DINNER
Day 2 - Monday 12 October

Session 2: Single-cell Approaches and Cell Biology
Chairs: Tâm Mignot and Teuta Plizota


Live from under the lens: On particle degradation and viral attack
Roman Stocker, ETH Zurich, Switzerland

09:25-09:40 The coupling of replication and cell division cycles in individual E. coli cells
Johan Elf, Uppsala University, Sweden
09:40-10:05 Illuminating bacteria
Mark C. Leake
, University of York, UK 
10:05-10:20 Metabolic coupling between different cell types during Bacillus subtilis sporulaiton
Javier Lopez Garrido, University of California, San Diego, USA
10:20-10:50 COFFEE BREAK
10:50-11:15 Interplay between membranes and MreB filaments
Jan Löwe
, MRC Laboratory of Molecular Biology, UK 
11:15-11:30 Cell division control in multichromomomal bacteria
François Xavier Barre, CNRS, France
11:30-11:55 Bactofilins: new players in the organization of bacterial cells
Martin Thanbichler
, MPI for Terrestrial Microbiology, Germany 
11:55-12:20 Relative rates of surface and volume synthesis set bacterial cell size
Julie Theriot
, Stanford University School of Medicine, USA 
12:20-15:15 LUNCH and POSTER SESSION 1 (Odd numbers)

Session 3: Chromosome dynamics and Regulation
Chairs: Carol Gross and Gene-Wei Li

15:15-15:40 How Bacteria Distinguish Self From Other
Bonnie Bassler
, Princeton University, USA
15:40-15:55 Fine tuning of the Cpx envelope stress response contributes to cell wall homeostasis in E. coli
Géraldine Laloux, de Duve Institute   University of Louvain (UCL), Belgium

Aerobic and anaerobic trimethylamine oxide signalling in E. coli
Mark Goulian
, University of Pennsylvania, USA

16:20-16:45 Bacterial adaptation to life on leaves
Julia Vorholt, ETH Zurich, Switzerland
16:45-17:15 COFFEE BREAK
17:15-17:40 How Schrodinger’s cat became a cat
Rob Phillips
, California Institute of Technology, USA 
17:40-17:55 Chemotaxis driven autoaggregation of Escherichia coli
Leanid Laganenka, Max Planck Institut für terrestrische Mikrobiologie, Germany
17:55-18:20 Understanding Bacterial Function on the Nanoscale: Capturing the dynamic search for rare DNA mismatches
Julie S. Biteen, University of Michigan, USA
18:20-18:35 Regulation of the topoisomerase IV activity by an oscillating intracellular redox
Sunish Radhakrishnan, Indian Institute of Science Education and Research, India

High throughput 4D single cell analysis reveals short and long time-scale E.coli nucleoid dynamics and their linkage to spindle-less sister segregation and chromosome/division coordination without a cell cycle engine
Nancy Kleckner, Harvard University, USA

19:00-20:30 DINNER 

Drinks in the ATC Roof Top Lounge

Day 3 - Tuesday 13 October

Session 4: Pathogenesis and Infection
Chairs: Pascale Cossart and Sam Miller

09:00-09:25 Interactions of Vibrio cholerae and virulent phages in the host
Andrew Camilli
, Sackler School of Graduate Biomedical Sciences, Tufts University, USA
09:25-09:40 Systems biology approaches unravel critical roles of microRNAs in bacterial infections
Ana Eulalio, University of Würzburg, Germany
09:40-10:05 Intracellular anchoring of Salmonella vacuoles
David Holden
, Imperial College London, UK

A mechano chemosensory system regulates virulence in Pseudomonas aeruginosa
Alexandre Persat, Princeton University, United States of America

10:20-11:00 COFFEE BREAK
11:00-11:25 Discrimination of pathogens from non-pathogens by innate immune cells
Jeffery Cox
, University of California, San Francisco, USA
11:25-11:40 ISG15 counteracts Listeria monocytogenes infection
Lilliana Radoshevich, Institut Pasteur, France
11:40-12:05 Remarkable Functional Convergence: Magic Spot Mediates Persistence by Activating Both Type I and II Toxin-Antitoxins
Kenn Gerdes, University of Copenhagen, Denmark 
12:05-15:15 LUNCH & POSTER SESSION 2 (Even numbers)
Session 5: Antibiotics
Chairs: Nassos Typas and Jean-François Collet
15:15-15:40 Antibiotic adjuvants to reclaim legacy drugs
Gerry Wright
, McMaster University, Canada
15:40-15:55 Iron deprivation inhibits late stages of bacterial cell division and arrests cytokinesis
Douglas Weibel, University of Wisconsin Madison, USA
15:55-16:20 Role of Fe-S clusters in bacterial sensitivity to antibiotics
Frédéric Barras, Aix Marseille University, France
16:20-16:35 Widespread ribo regulation of antibiotic resistance in the human microbiome
Daniel Dar, Weizmann Institute of Science, Israel
16:35-16:50 Frequency of antibiotic application dictates rapid evolutionary adaptation of bacterial persistence
Jan Michiels, KU Leuven, Belgium
16:50-17:20 COFFEE BREAK
17:20-17:45 Identification of MltG as a potential terminase for peptidoglycan polymerization in bacteria
Thomas Bernhardt
, Harvard Medical School, USA
17:45-18:00 A dynamin like protein involved in bacterial cell membrane surveillance under environmental stress
Marc Bramkamp, LMU Munich, Germany

How antibiotics induce competence for genetic transformation
Jan-Willem Veening, University of Groningen, The Netherlands

18:25-18:40 Correlating emergent ultrastructural membrane phenomena with beta lactam target specificity
Daniel Dwyer, University of Maryland, USA
19:00-20:30 SPECIAL DINNER
Day 4 - Wednesday 14 October
Session 6: Bacterial Communities -Microbiome
Chairs: Urs Jenal and Rotem Sorek

09:00-09:25 KC Huang, Stanford University, USA 
09:25-09:40 Killing for DNA: The type VI secretion system of Vibrio cholerae fosters horizontal gene transfer
Melanie Blokesch, Swiss Federal Institute of Technology Lausanne, Switzerland
09:40-10:05 The human intestinal microbiome in health and disease – dysbiosis revisited
Joël Doré
, INRA, France
10:05-10:20 Growth dynamics of gut microbiota in health and disease inferred from single metagenomic samples
Tal Korem, Weizmann Institute of Science, Israel
10:20-10:50 COFFEE BREAK
10:50-11:15 Gut Microbiota and Type 2 Diabetes
Fredrik Bäckhed
, University of Gothenburg, Sweden
11:15-11:30 Eco systems Biology of the Global Ocean Microbiome
Shinichi Sunagawa, EMBL Heidelberg, Germany
11:30-11:55 Host microbiome interactions in health and disease
Eran Elinav
, Weizzman Institute of Science, Israel
11:55-12:10 Dynamics of cell sorting in early biofilms
Berenike Maier, University of Cologne, Germany
12:10-15:00 LUNCH and POSTER SESSION 3 (Odd and Even numbers)
Session 7: Evolution
KC Huang and Kiran Patil
15:00-15:25 Cooperation and competition in microbial communities
Kevin Foster
, University of Oxford, UK
15:25-15:40 The contributions to phenotypic variation across Escherichia coli strains
Pedro Beltrao, EMBL EBI, United Kingdom
15:40-16:05 Choanoflagellate colonies, bacterial signals, and animal origins
Nicole King
, University of California, Berkeley, USA
16:05-16:20 Unraveling the functional basis of chemical tolerance in evolved strains of Escherichia coli
Rebecca Lennen, Technical University of Denmark, Denmark
16:20-16:45 Bacterial survival strategies in dynamic environments
Martin Ackermann
, ETH Zurich, Switzerland
16:45-17:00 Defeating cheater exclusion in biofilms via general adaptation rather than by specific adjustment
Akos Kovacs, Friedrich Schiller University Jena, Germany
17:00-17:15 Poster Awards and Concluding remarks
17:15-18:15 FAREWELL with Wine and Cheese
18:20 Buses to Frankfurt Airport and Heidelberg Downtown