Location & dates EMBL Heidelberg, Germany 14 - 17 May 2018
Deadlines Registration closed Abstract submission closed
EES_logo

EMBL Courses and Conferences during the Coronavirus pandemic

With the onsite programme paused, many of our events are now being offered in virtual formats.


Registration is open as usual for many events, with back-up plans in place to move further courses and conferences online as necessary. Registration fees for any events affected by the COVID-19 disruption are fully refundable.


More information for participants of events at EMBL Heidelberg can be found here.

Programme

Got something to say? Tweet it! #EESliquidphase

Day 1 - Sunday 13 May 2018 (PhD /Postdoc Summit only)
TimePhD /Postdoc Summit for selected students only
12.15-13.15 Arrival / Registration for Summit with light refreshments
13.15-13.30 Opening remarks
13.30-14.30

Introduction

14.30-19.00 Talks including discussion
14.30-15.15

IDPs by Edward Lemke

15.15-16.00 LLPs by Clifford Brangwynne
16.00-16.30

Coffee Break

16.30-17.15 LLPs in disease by Tanja Mittag
17.15-18.00 LLPs in DevBio by Carl-Philipp Heisenberg
18.00-19.00

Working groups to prepare talks for next day

19.00-21.00

Poster Session with light refreshments

Day 2 - Monday 14 May 2018 (1st Day of Symposium)
TimePhD /Postdoc Summit for selected students only
09.00-10.00 Student talks
10.00-10.30

Coffee Break

10.30-11.30

Student talks

11.30-13.00

Lunch

13.00-13.45

Editor Roundtable discussion (Hurtley, Shadan, Szewczak, Rembold, Nielsen)

13.45-14.45

Student talks

14.45-15.15 Coffee Break
15.15-16.15 Student talks
16.15-16.45 Coffee Break
16.45-17.45 Senior Cell Editor talk including discussion in Courtyard Seminar Room (open to all participants)
17.45-19.15Arrival / Registration for Symposium with light refreshments
19.15-19.30

Opening remarks

19.30-20.30

Keynote: Biomolecular condensates: Organizers of cellular biochemistry
Anthony Hyman, Max Planck Institute of Molecular Cell Biology and Genetics

Chair: Clifford P. Brangwynne, Princeton University

20.30-22.30 Welcome reception and Poster session I (odd numbers)
Day 3 - Tuesday 15 May 2018
TimeSpeaker
08.55-12.00 Session 1 - The pathological face of phase separation
Chair: Stella M. Hurtley, Senior Editor Science

08.55-09:00 Introduction by session chair
09.00-09.30 Physiological and Pathological Phase Separation of FUS is Regulated by Methylation of Cooperative Cross-Domain Cation-Pi Interactions and interaction with TNPO1
Peter St George-Hyslop, University of Cambridge
09.30-10.00 EMBO Young Investigator Lecture: The role of cellular stress in the initiation of TDP-43 and FUS pathology
Magdalini Polymenidou, University of Zurich
10.00-10.12 Selected talk: Lindsay Becker, Stanford University
10.12-10.24 Selected talk: Jill Bouchard, St. Jude Children's Research Hospital
10.24-10.36

Selected talk: Mario Hofweber, LMU Munich

10.36-11.00

Coffee Break & Meet the Speakers (St George-Hyslop, Polymenidou, Hyman)
and Editors

11.00-11.12

Selected talk: Kiersten Ruff, Washington University in St. Louis

11.12-11.24

Selected talk: Ludo Van Den Bosch, KU Leuven & VIB

11.24-11.36 Selected talk: Elke Roovers, Institute of Molecular Biology (IMB)
11.36-11.48 Selected talk: Benjamin Sabari, Whitehead Institute for Biomedical Research
11.48-12.00 Selected talk: Tatjana Trcek, HHMI, Skirball Institute, NYU
12.00-13.30 Lunch in ATC Foyer
13.30-16.30

Session 2 - Molecular function of phase separation
Chair: Sadaf Shadan, Senior Editor Nature

13.30-13.35

Introduction by session chair

13.35-14.05

Gel or die: phase separation as a survival strategy
Simon Alberti, Max Planck Institute of Molecular Cell Biology and Genetics

14.05-14.35

Kinase-controlled phase transition of membrane-less organelles during mitosis
Lucas Pelkmans, University of Zurich

14.35-15.05

HSPB2 forms nuclear compartments that affect lamin A and compromise nuclear function
Serena Carra, University of Modena and Reggio Emilia

15.05-15.30

Coffee Break & Meet the Speakers (Alberti, Pelkmans, Carra)

15.30-15.42

Selected talk: Giorgia Celetti, EMBL Heidelberg

15.42-15.54

Selected talk: David Drummond, The University of Chicago

15.54-16.06

Selected talk: Christiane Iserman, Max Planck Institute of Molecular Cell Biology and Genetics

16.06-16.18

Selected talk: Aristeidis Sfakianos, University of Manchester

16.18-16.30

Selected talk: Shayan Shamipour, Institute of Science and Technology

16.30-18.30

Poster session II (even numbers)

18.30-20.00

Dinner in EMBL canteen

20.00-21.30 After-dinner drinks in ATC Foyer
Day 4 - Wednesday 16 May 2018
TimeSpeaker
08.55-12.00 Session 3 - Phase separation, a polymer physics perspective
Chair: Edward Lemke, EMBL Heidelberg, IMB & JGU Mainz
08.55-09:00 Introduction by session chair
09.00-09.30

A stickers and spacers framework for phase transitions of multivalent proteins
Rohit V. Pappu, Washington University in St. Louis

09.30-10.00

Universal features in phase separation: Implications for stress granule formation
Chiu Fan Lee, Imperial College London

10.00-10.30

Phase separation in active systems
Frank Jülicher, Max Planck Institute for the Physics of Complex Systems

10.30-11.00

Coffee Break & Meet the Speakers (Pappu, Lee, Jülicher)
and Editors

11.00-11.12

Selected talk: Randal Halfmann, Stowers Institute for Medical Research

11.12-11.24

Selected talk: Jasper Michels, Max Planck Institute for Polymer Research

11.24-11.36

Selected talk: Daisuke Mizuno, Kyushu University

11.36-11.48

Selected talk: Raghav Poudyal, Pennsylvania State University

11.48-12.00 Selected talk: Shambaditya Saha, Max Planck Institute of Molecular Cell Biology and Genetics
12.00-12.30 Packed lunch in ATC Foyer
12.30-17.00 Free afternoon / sightseeing (Buses to Heidelberg´s Old Town and funicular railway station for optional castle visits - see bus schedule)
17.00-19.00 Session 4 - Phase separation in developmental biology and non-linear signaling
Chair: Lara Szewczak, Senior Editor Cell
17.00-17.05

Introduction by session chair

17.05-17.35

RNA granules: liquid or active condensates?
Geraldine Seydoux, Johns Hopkins University School of Medicine

17.35-18.05

The Dishevelled paradigm – signalosome assembly in animals and plants
Mariann Bienz, MRC Laboratory of Molecular Biology

18.05-18.35

Stress assemblies in Drosophila by nutrient deprivation
Catherine Rabouille, Hubrecht Institute

18.35-18.47

Selected talk: Elliot Dine, Princeton University

18.47-19.00

Selected talk: Andrea Putnam, Johns Hopkins University School of Medicine

19.00-19.30

Pre-dinner drinks & Meet the Speakers (Seydoux, Bienz, Rabouille)

19.30-21.00

Dinner in EMBL canteen

21.00-22.30

After-dinner drinks in ATC Rooftop Lounge

Day 5 - Thursday 17 May 2018
TimeSpeaker
08.55-12.12

Session 5 - Liquid compartments in the cell
Chair: Simon Alberti, Max Planck Institute of Molecular Cell Biology and Genetics

08.55-09.00

Introduction by session chair

09.00-09.30

RNA structure and specificity in cellular phase separation
Amy S. Gladfelter, The University of North Carolina at Chapel Hill

09.30-10.00

Mechanisms of heterochromatin assembly and function
Geeta Narlikar, University of California, San Francisco

10.00-10.12

Sara Cuylen-Häring, EMBL Heidelberg, Germany

10.12-10.24

Gregory Dignon, Lehigh University, USA

10.24-11.00

Coffee Break & Meet the Speakers (Gladfelter, Narlikar)
and Editors

11.00-11.12

Selected talk: Dan Bracha, Princeton University

11.12-11.24

Selected talk: Owen Andrews, MIT

11.24-11.36

Selected talk: Felipe Garcia Quiroz, The Rockefeller University

11.36-11.48

Selected talk: Martin Jonikas, Princeton University

11.48-12.00 Selected talk: Matthew King, Princeton University
12.00-12.12 Selected talk: Erin Langdon, University of North Carolina at Chapel Hill
12.12-13.45 Lunch in ATC Foyer
13.45-16.45 Session 6 - Protein structure in the condensed state
Chair: Tanja Mittag, St. Jude Children's Research Hospital
13.45-13.50

Introduction by session chair

13.50-14.20

FMRP phase separation in activity-dependent translation
Julie D. Forman-Kay, The Hospital for Sick Children

14.20-14.50

Abnormal Phase Separation in Neurodegeneration and Cancer
Richard W. Kriwacki, St. Jude Children's Research Hospital

14.50-15.20

Single-Molecule and Polymer Physics views of Liquid Phase Separation
Ashok Deniz, The Scripps Research Institute

15.20-15.50

Coffee Break & Meet the Speakers (Forman-Kay, Kriwacki, Deniz, Rosen)

15.50-16.02

Selected talk: Nicolas Fawzi, Brown University

16.02-16.14 Selected talk: Beatriz Gomes, Max Planck Institute of Molecular Cell Biology and Genetics
16.14-16.26

Selected talk: Timothy Nott, University of Oxford

16.26-16.45

Feedback Survey Session

16.45-17.00

Coffee Break

17.00-18.00

Keynote: Composition-dependent functions of biomolecular condensates
Michael K. Rosen, UT Southwestern Medical Center/HHMI

Chair: Carl-Philipp Heisenberg, Institute of Science and Technology Austria

18.00-18.15

Closing remarks

18.15-18.30

Pre-dinner drinks

18.30-20.30

Conference Dinner

20.30-00.00

Conference Party with DJ