Location & dates EMBL Heidelberg, Germany 27 - 30 May 2018
Deadlines Registration closed Abstract submission closed
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Programme

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LIST OF POSTERS - MICROTUBULES SYMPOSIUM 2018

Day 1 - Sunday 27 May 2018
TimeSpeaker
12:00 - 14:00  Arrival and registration
14.00-15.55 Session 1 - Microtubule motors and complex motor assemblies 
Chair: Richard McKenney
14.00-14.10 Opening remarks
14.10-14.35

The 3.5Å cryo-EM structure of a fast dynein/dynactin complex
Andrew Carter - MRC LMB Cambridge, UK

14.35-15.00

Regulation of microtubule-based transport 
Samara Reck-Peterson - University of California, San Diego, USA

15.00-15.25

Microtubule motors in sensory neurons of C. elegans
Guangshuo Ou - Tsinghua University, Beijing, China

15.25-15.40

In vitro reconstitution of kinesin-based mRNA transport
Sebastian Maurer - Center for Genomic Regulation (CRG), Spain   

15.40-15.55

Cargo adaptors regulate the force generation and speed of the mammalian dynein/dynactin complex
Ahmet Yildiz - University of California Berkeley, United States of America

15.55-16.25 Coffee Break and Meet the Speakers
16.25-17.55 Session 2 - Centrioles and cilia 
Chair: Paul Conduit
16.25-16.50

Centriole birth and death
Monica Bettencourt-Dias - Instituto Gulbenkian de Ciência, Oeiras, Portugal

16.50-17.15

Intraflagellar transport is restricted to specific microtubule doublets
Philippe Bastin - Institut Pasteur, Paris, France

17.15-17.40

Active transport of signalling receptors across the ciliary diffusion barrier
Maxence Nachury - University of California, San Francisco, USA

17.40-17.55

The Cryo-EM structure of Intraflagellar Transport Trains reveals how its motors avoid engaging in a tug-of-war
Gaia Pigino - Max Planck Institute CBG, Germany 

18.00-19.30

Dinner in the EMBL canteen

19.30-21.00 Speed networking session (ATC Foyer)
19.30-23.00 Welcome reception with beer and wine and preview of all posters
Day 2 - Monday 28 May 2018
TimeSpeaker
09.00-10.00

Keynote lecture
Chair: Anna Akhmanova
Eva Nogales - HHMI, University of California, Berkeley, USA

A sharper view of microtubule structure and interactions

10.00-10.30 Coffee Break
10.30-12.15

Session 3 - Microtubule diversity, dynamics and drugs 
Chair: Naoko Mizuno

10.30-10.55

Microtubule cryptography: the effects of tubulin diversity on polymer structure and dynamics
Antonina Roll-Mecak - NIH, Bethesda, USA

10.55-11.20

Mechanism and regulation in microtubule dynamics
Luke Rice - UT Southwestern, Dallas, USA

11.20-11.45

Tubulin domain structure and regulation of microtubule dynamics
Maria Kavallaris - Children’s Cancer Institute, Sydney, Australia

11.45-12.00

Cryo electron tomography and computational modeling reveal a new mechanism of microtubule assembly
Nikita Gudimchuk - Lomonosov Moscow State University, Russian Federation       

12.00-12.15

Probing microtubule dynamic instability with doublecortin and cryo-EM
Szymon Manka - Institute of Structural and Molecular Biology, Birkbeck College London, United Kingdom

12.15-14.00

Lunch and Meet the Editors and Meet the Speakers

14.00-15.00

Session 4 - Emerging topics 1
Chair: Julie Welburn

14.00-14.15

Towards a comprehensive understanding of the MAP code
Kassandra Ori-McKenney - UC Davis, United States of America

14.15-14.30

The spindle protein CKAP2 is a potent microtubule growth factor
Susanne Bechstedt - McGill University, Canada 

14.30-14.45

Tau molecules diffusing on microtubules can establish high-density Tau patches that dynamically grow and shrink
Marcus Braun - IBT CAS Centrum BIOCEV, Czech Republic  

14.45-15.00

CLASP mediates microtubule tip and lattice repair through a single TOG domain
Amol Aher - Utrecht University, The Netherlands 

15.00-15.20

Poster flash talks (11 talks)

Abstract no. 71- Chan, Jordi
Abstract no. 87- Eshun-Wilson, Lisa
Abstract no. 93- Freal, Amelie
Abstract no. 107- Hannabuss, Jonathon
Abstract no. 129- Kolenda, Caroline
Abstract no. 181- Redemann, Stefanie
Abstract no. 187- Saltini, Marco
Abstract no. 207- Spreng, Benjamin
Abstract no. 237- Yamada, Moé
Abstract no. 239- Zabeo, Davide
Abstract no. 243- Zenker, Jennifer

15.20-15.50

Coffee Break

15.50-18.30

Poster session 1 (odd numbers)

18.30-19.55

Dinner in the EMBL Canteen

20.00-20.40

1st Landmark lecture:
Chair: Carsten Janke

Much ado about microtubules
Tony Hyman - Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany

20.45-22.30 Wine and beer session with the possibility to continue poster session
Day 3 - Tuesday 29 May 2018
TimeSpeaker
09.00-10.45 Session 5 - Microtubule nucleation 
Chair: Sabine Petry
09.00-09.25 Mechanisms of microtubule nucleation
Elmar Schiebel - ZMBH, University of Heidelberg, Germany
09.25-09.50

The relationship between microtubule birth and death
Gary Brouhard - McGill University, Montreal, Canada

09.50-10.15

Regulation of Golgi-derived microtubule nucleation
Irina Kaverina - Vanderbilt University, Nashville, Tennessee, USA

10.15-10.30

A two-step mechanism for the inactivation of MTOC function at the centrosome
Jessica Feldman - Stanford University, United States of America

10.30-10.45

Autocatalytic microtubule nucleation determines the size and mass of spindles
Franziska Decker - MPI-PKS / MPI-CBG, Dresden, Germany

10.45-11.15 Coffee Break
11.15-12.30 Session 6 - Emerging topics 
Chair: Marija Zanic
11.15-11.30

Deregulation of tubulin polyglutamylation induced neurodegeneration in mice and humans
Maria Magiera - Institut Curie, PSL Research University, Universite Paris-Saclay, France

11.30-11.45

Large scale genomic and bioinformatic approaches reveal the interphase Microtubule Integrity Response (MIR)
Ivana Gasic - Harvard Medical School, United States of America

11.45-12.00

Amoeboid Migration Along the Path of Least Resistance by a Nuclear Mechanical Gauge Mechanism Coordinated by Microtubules
Jörg Renkawitz  - Institute of Science and Technology (IST), Austria                  

12.00-12.15

Motor axon navigation relies on fidgetin-like 1-driven microtubule plus-end dynamics
Coralie Fassier  - Sorbonne Universités, Institut de Biologie Paris-Seine, France

12.15-12.30

Formation and Function of Noncentrosomal Microtubule Arrays in the Epidermis
Terry Lechler - Duke University, United States of America

12.30-14.00

Lunch and Meet the speakers 

14.00-14.40

2nd Landmark lecture:
Chair: Gohta Goshima
Kinesins at the crossroads of microtubule organization and assembly

Linda Wordeman - University of Washington, Seattle, USA

14.40-15.00

Poster flash talks (9 talks)

Abstract no. 54- Ivana Ban
Abstract no. 90- Ferreira, Jorge
Abstract no. 92- Firat-Karalar, Elif Nur
Abstract no. 106- Hahn, Ines
Abstract no. 132- Kruger, Lara
Abstract no. 134- Kuzmic, Barbara
Abstract no. 158- Nashchekin, Dmitry
Abstract no. 164- Orbach, Ron
Abstract no. 228- Al-Bassam, Jawdat

15.00-15.30

Coffee Break

15.30-18.30

Poster session 2 (even numbers)

18.30-19.30

Round table : Research in emerging regions and countries
(Moderator: Gerlind Wallon, Luis Valente, Maria Leptin)

Christian Gonzalez Billault - Universidad de Chile, Santiago, Chile
Krishanu Ray - TIFR, Mumbai, India
Guangshuo Ou - Tsinghua University, Beijing, China
Maria Kavallaris - Children’s Cancer Institute, Sydney, Australia
Patricia Garcez - Federal University of Rio de Janeiro, Brazil

19.30-00.00 BBQ Dinner with follow-up party in the EMBL Canteen
Day 4 - Wednesday 30 May 2018
TimeSpeaker
09.30-11.15 Session 7 - Neuronal microtubules, motors and MAPs 
Chair: Andreas Prokop
09.30-09.55

Sorting out polarized transport in neurons
Lukas Kapitein - University of Utrecht, The Netherlands

09.55-10.20

MAP6 proteins: keys actors of neuronal actin and microtubule organization
Annie Andrieux - Grenoble Institute of Neurosciences, Grenoble, France

10.20-10.45

Mechanism of synaptic activity-dependent feedback regulation of the axonal transport by Kinesin-2
Krishanu Ray - TIFR Mumbai, India

10.45-11.00

Microtubule-destabilizing protein CENPJ is required for neuronal development
Patricia Garcez - Federal University of Rio de Janeiro, Brazil

11.00-11.15

NEK7 regulates dendrite morphogenesis in neurons via Eg5-dependent microtubule stabilization
Jens Lüders - Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Spain                    

11.15-11.45 Coffee Break
11.45-13.20 Session 8 - Microtubules in cell division
Chair: Alex Bird
11.45-12.10

A novel microtubule nucleation pathway for meiotic spindle assembly in oocytes
Hiro Ohkura - The University of Edinburgh, UK

12.10-12.35

Kinetochores get a grip
Trisha Davis - University of Washington, Seattle, USA

12.35-12.50

Microtubule Dynamics Scale with Cell Size to Set Spindle Length and Assembly Timing
Julien Dumont  - CNRS - Institut Jacques Monod, France

12.50-13.05

Towards a spindle steady-state: contractile and extensile microtubule networks
Christina Hueschen - UCSF, United States of America

13.05-13.20

Optogenetic reconstitution reveals that Dynein-Dynactin-NuMA clusters generate cortical spindle-pulling forces as a multi-arm ensemble
Tomomi Kiyomitsu - Nagoya University, Japan

13.20-14.40

Lunch and Meet the Speakers

14.40-14.55

Poster prizes

14.55-16.40

Session 9 - Microtubule mechanics and forces 
Chair: Melissa Gardner

14.55-15.20

Microtubule-dependent positioning of the nucleus in the C. elegans embryo
Akatsuki Kimura - National Institute of Genetics, Mishima, Japan

15.20-15.45

Plant shapes impact microtubule behaviour
Olivier Hamant - ENS Lyon, France

15.45-16.10

EMBO Young Investigator Lecture - Microtubule shaft dynamics
Manuel Thery - Hôpital St. Louis, Paris, France

16.10-16.25

Force-induced control of microtubule dynamics by oligomeric kinetochore module 
Vladimir Volkov - Delft University of Technology, The Netherlands

16.25-16.40 Highly-parallel, microfluidics-based force-velocity measurements on single motor proteins
Stefan Diez - B CUBE, Technische Universität Dresden, Germany
16.40-16.50 Closing remarks