Location & dates EMBL Heidelberg, Germany 3 - 6 Jul 2019
Deadlines Registration closed Abstract submission closed
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Programme

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Day 1 - Wednesday 3 July 2019
TimeSpeaker
11:30 – 13:15 Registration and Lunch
13:15 – 13:30 Opening Remarks
13:30 – 14:30

Keynote Lecture
Thomas Lecuit - The Developmental Biology Institute of Marseille (IBDM), France

14:30 - 18:00 

Scientific Session 1 - Tissue Mechanics
Chair: Frank Schnorrer

14:30 – 15:00

Dynamics establishment of morphogen gradient in the early Drosophila embryo
Naama Barkai - Weizmann Institute of Science, Israel

15:00 – 15:30

Olivier Pourquié - Harvard University, USA

15:30 – 16:30

Coffee Break and Meet the Speakers

16:30 – 16:45

Epithelial viscoelasticity is regulated by mechanosensitive E-Cadherin turnover
Venkatesan Iyer - Max Planck Institute of Molecular Cell Biology and Genetics, Germany

16:45 – 17:00 

Mechanical coordination directs tissue replacement during metamorphosis in drosophila 
Enrique Martin-Blanco - IBMB (CSIC), Spain

17:00 – 17:15

Control of tissue morphogenesis by Drosophila Ultrabithorax
Maria-Carmen Diaz-de-la-Loza - The Francis Crick Institute, UK

17:15 – 17:30 

Role of mechanosensitive ion channel (TMC) in coordinated epithelial cell dynamics in Drosophila embryos
Prachi Richa - Universitätsmedizin Göttingen, Germany

17:30 – 17:45

Cytoskeletal tension and Bazooka/Par3 tune interface geometry to ensure fusion fidelity and sheet integrity during Drosophila dorsal closure
Maithreyi Narasimha - Tata Institute of Fundamental Research, India

17:45 – 18:00

Mechanical symmetry breaking drives fate specification during heart morphogenesis
Rashmi Priya - Max Planck Institute for Heart and Lung Research, Germany

18:00 – 19:00 Poster Preview Session
19:00 – 20:30

Dinner in the EMBL Canteen

20:30 – 23:00 Welcome reception in the ATC Rooftop Lounge
Day 2 -  Thursday 4 July 2019
TimeSpeaker
09:00 - 12:30 Scientific Session 2: Cellular Mechanics
Chair: Naama Barkai
09:00 – 09:30

Folding and collective migration
Yohanns Bellaïche - Institut Curie, France

09:30 – 10:00

Mechanosensation of tight junctions by ZO-1 phase separation and flow
Carl-Philipp Heisenberg - Institute of Science and Technology, Austria

10:00 – 10:30

Mechanical stress regulates epithelial tissue integrity during Xenopus embryogenesis
Naoto Ueno - National Institute for Basic Biology, Japan

10:30 – 11:00

General tissue properties influence nuclear positioning in neuroepithelia
Caren Norden - Max Planck Institute of Molecular Cell Biology and Genetics, Germany

11:00 – 11:30

Coffee Break and Meet the Speakers

11:30 – 11:45 

Morphogenesis is stressful – elasticity and mechanics of folding cell sheets
Stephanie S.M.H. Höhn - University of Cambridge, UK

11:45 – 12:00

Scaling of PeCoWaCo (periodic cortical waves of contraction)
Ozge Ozguc - Institut Curie, France

12:00 – 12:15

Selective Filopodia adhesion ensures robust cell matching in the Drosophila heart 
Timothy Saunders - Mechanobiology Institute, Singapore

12:15 – 12:30

Mechanosensitive control of cytoskeletal and cell dynamics by the physical tissue environment
Verena Ruprecht - Centre for Genomic Regulation - CRG, Spain

12:30 – 14:00

Lunch

13:00 – 14:00 

ERC: Funding Opportunities for Top Researchers from Anywhere in the World
Moderators: 
Mariam Benjdia - European Research Council, Eduardo Moreno - Champalimaud Centre for the Unknown, Caren Norden - Max Planck Institute of Molecular Cell Biology and Genetics 

14:00 - 17:30

Scientific Session 3: Mechanosensation
Chair: Carl-Philipp Heisenberg

14:00 – 14:30

Mechanical cell competition during development and cancer 
Eduardo Moreno - Champalimaud, Portugal

14:30 – 15:00

Muscle contractions pattern epithelial morphogenesis: mechanosensing and mechanotransduction
Michel Labouesse - Institute of Biology Paris-Seine, France

15:00 – 15:30

Biomechanics of muscle building - timing of myofibrillogenesis
Frank Schnorrer - The Developmental Biology Institute of Marseille (IBDM), France

15:30 – 16:00

Mechanosensing by the developing lamina protects against nuclear rupture, DNA damage, and cell cycle arrest
Dennis Discher - University of Pennsylvania, USA

16:00 – 16:30

Coffee Break and Meet the Speakers

16:30 – 16:45

Stem cell dynamics and signalling in response to force-mediated skin expansion
Mariaceleste Aragona - Université Libre de Bruxelles, Belgium

16:45 – 17:00

Directing growth of cell collectives by photoactivation of YAP
Hanna Engelke - Ludwig-Maximilians-Universität München, Germany

17:00 – 17:15

Mechanosensation-dependent Ca2+ dynamics during atrioventricular valve development
Hajime Fukui - Institute of Genetics and Molecular and Cellular Biology (IGBMC), France

17:15 – 19:00 Poster Session 1 (odd numbers) 
19:00 – 20:30

Dinner in the EMBL Canteen

20:30 – 23:00 After dinner drinks in the ATC Rooftop Lounge
Day 3 - Friday 5 July 2019
TimeSpeaker
09:00 - 12:30 Scientific Session 4: Modelling Cell Mechanics and Signalling
Chair: Michel Labouesse
09:00 – 09:30 Resolving Conflicts: The Genetic Control of Morphogenesis
Enrico Coen - John Innes Centre, UK
09:30 – 10:00

Active material properties of dynamic tissue
Frank Jülicher - Max Planck Institute for the Physics of Complex Systems, Germany

10:00 – 10:30

Physics of epithelial folds and flows
Guillaume Salbreux - The Francis Crick Institute, UK

10:30 – 11:00

Dynamic coupling of cell adhesion, RhoA signaling and actomyosin contractility drives zippering and neural tube closure in a simple chordate
Edwin Munro - The University of Chicago, USA

11:00 – 11:30

Coffee Break and Meet the Speakers

11:30 – 11:45 

Theory of mechanochemical patterning in biphasic biological tissues
Adrien Hallou - University of Cambridge, UK

11:45 – 12:00

Minimisation of surface energy drives apical epithelial organisation and gives rise to Lewis’ law
Marco Kokic - Swiss Federal Institute of Technology in Zurich, Switzerland

12:00 – 12:15

Upscaling active gel models of the actin cortex to epithelial mechanics
Adam Ouzeri - Polytechnic University of Catalonia, Spain

12:15 – 12:30

Development and mechanics of malaria-infected red blood cells
Ulrich Schwarz - Heidelberg University, Germany

12:30 – 14:00

Lunch

13:00 – 14:00 

Meet the Editors
Moderators: 
Ieva Gailite - The EMBO Journal, Christina Karlsson Rosenthal - Communications Biology, Nina Vogt - Nature Methods

14:00 - 17:30

Scientific Session 5: Cytoskeletal Mechanics
Chair: Enrico Coen

14:00 – 14:30

Mechanosensing at the adherens junction
Beth Pruitt - University of California, Santa Barbara, USA

14:30 – 15:00

How neurons bend without breaking
Miriam Goodman - Stanford University, USA

15:00 – 15:30

Dynamin bundles actin filaments to promote invasive protrusions in cell-cell fusion
Elisabeth Chen - The University of Texas Southwestern Medical Center, USA

15:30 – 16:00

RhoA Mediates Epithelial Cell Shape Changes via Mechanosensitive Endocytosis
Margaret Gardel - The University of Chicago, USA

16:00 – 16:30

Coffee Break and Meet the Speakers

16:30 – 16:45

Interkinetic nuclear migration - a stochastic process constrained by tissue architecture
Anne Herrmann - University of Cambridge, UK

16:45 – 17:00

Planar Cell Polarity signalling coordinates heart tube remodelling through tissue-scale polarisation of actomyosin activity
Daniela Panáková - Max Delbrück Center for Molecular Medicine, Germany

17:00 – 17:15

Tissue-scale mechanical coupling reduces morphogenetic noise to ensure precision during epithelial folding
Yu-Chiun Wang - RIKEN, Japan

17:15 – 17:30

Tissue self-organized mechanical forces in intestinal organoid crypt morphogenesis
Qiutan Yang - Friedrich Miescher Institute for Biomedical Research, Switzerland

17:30 – 19:00

Poster Session 2 (even numbers) 

19:00 – 20:30

Conference Dinner in the EMBL Canteen

20:30 – 00:00 Conference Party
Day 4 - Saturday 6 July 2019
TimeSpeaker
09:00 - 13:00 Scientific Session 6: Tissue Morphogenesis
Chair: Thomas Lecuit
09:00 – 09:30

Transformation, extrusion and the mechanical epithelial environment
Alpha Yap - The University of Queensland, Australia

09:30 – 10:00

Can gene expression domains be used to predict 3D morphogenesis in flowers?
Henrik Jönsson - University of Cambridge, UK

10:00 – 10:30

Comparative approach to tissue morphogenesis in insects - a new force awakens
Pavel Tomancak - Max Planck Institute of Molecular Cell Biology and Genetics, Germany

10:30 – 11:00

Cell shape changes in a folding epithelium: genetically and mechanically determined boundaries
Maria Leptin - EMBL Heidelberg, Germany

11:00 – 11:30

Coffee Break and Meet the Speakers

11:30 – 11:45 

Morphogenesis and mechanotransduction in the closest evolutionary relatives of animals
Thibaut Brunet - HHMI/University of California, Berkeley, USA

11:45 – 12:00

Imaging and dynamic analysis of post-implantation mouse embryo development from gastrulation to early organogenesis using light-sheet microscopy
Kate McDole - HHMI - Janelia Research Campus, USA

12:00 – 13:00 Keynote Lecture
Ewa Paluch - Cambridge University, UK
13:00 – 13:15

Closing Remarks

13:15 – 13:30

Packed Lunch and Departure

13.30

Bus to Heidelberg downtown
Bus to Frankfurt Airport