Location & dates EMBL Heidelberg, Germany 20 - 23 Nov 2019
Deadlines Registration closed Abstract submission closed
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EMBL Courses and Conferences during the Coronavirus pandemic

With the onsite programme paused, many of our events are now being offered in virtual formats.


Registration is open as usual for many events, with back-up plans in place to move further courses and conferences online as necessary. Registration fees for any events affected by the COVID-19 disruption are fully refundable.


More information for participants of events at EMBL Heidelberg can be found here.

Programme

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Day 1 - Wednesday 20 November 2019
TimeSpeaker
11:00-13:15 Arrival and Registration
13:15-13:30 Opening remarks
13:30-14:30

Keynote Lecture 1: Metabolic-epigenetic axis in memory programming and disease
Shelley Berger - University of Pennsylvania, USA 

14:30-18:15

Session 1: Metabolism
Chair: Erika Pearce - Max Planck Institute of Immunobiology and Epigenetics, Germany

14:30-15:00

Transcriptional networks and epigenomic mechanisms driving lineage determination of human mesenchymal stem cells
Susanne Mandrup - University of Southern Denmark, Denmark

15:00-15:30

Metabolism, chromatin and transcription during a metabolic cycle
Jane Mellor - University of Oxford, UK

15:30-16:00

Coffee Break & Meet the Editors

16:00-16:30

Epigenetic modifications on chromatin: more or less than meets the eye?
Benjamin Tu - University of Texas Southwestern Medical Center, USA

16:30-17:00

Glycolytic flux control of mouse embryo segmentation
Hidenobu Miyazawa - EMBL Heidelberg, Germany 

17:00-17:15

Selected Short Talk: Riboregulation of Glycolysis via Human Enolase1
Ina Huppertz - EMBL Heidelberg, Germany

17:15-17:30

Selected Short Talk: Discovering key metabolic and bioenergetic signaling molecules during mitochondrial dysfunction
Yeyun Ouyang - Univeristy of Utah, USA

17:30-17:45

Selected Short Talk: Metabolic competition between phospholipid synthesis and histone methylation controls sexual differentiation in malaria parasites
Björn Kafsack - Weill Cornell Medical College, USA 

17:45 - 18:00

Selected Short Talk: NAD synthesis in glioblastoma cells
Christiane Opitz - German Cancer Research Center (DKFZ), Germany

18:00 -18:15

Selected Short Talk: Glutamine metabolism controls chondrocyte fate and function during bone development
Steve Stegen - KU Leuven, Belgium

18:15-20:15

Dinner in the EMBL Canteen 

20:15-22:00

Poster "Sneak Preview", Helix A (all numbers)

21:00 - 22:00

Welcome Drinks in the ATC Rooftop Lounge

19:00, 20:00,
21:00, 22:00

Bus departure

Day 2 - Thursday 21 November 2019
TimeSpeaker
 09:00-12:00 Session 2: Epigenetics
Chair: Jane Mellor - University of Oxford, UK
09:00-09:30

MOF histone acetyl transferase containing NSL complex linking epigenetics and metabolism
Asifa Akhtar - Max Planck Institute of Immunobiology and Epigenetics, Germany

09:30-10:00

Histone Crotonylation Links Metabolism to Gene Expression
Ashby Morrison - Stanford University, USA 

10:00-10:30

A NAD Metabolite Triggers the Allosteric Activation of the Chromatin Remodeling Oncogene ALC1/CHD1L
Andreas Ladurner - Ludwig Maximilian University of Munich, Germany 

10:30-11:00

Coffee Break

11:00-11:15

Selected Short Talk: Repression of Mammalian Promoters by Methylation-Directed O-Glycosylation of Chromatin Factors
Matthieu Boulard - EMBL Rome, Italy

11:15-11:30

Selected Short Talk: Histone variants link metabolism to 3D chromatin architecture
Marcus Buschbeck - Josep Carreras Leukaemia Research Institute, Spain

11:30-11:45 Selected Short Talk: Modulation of human mitochondrial metabolism by novel lysine-specific methyltransferases
Pål Falnes - University of Oslo, Norway
11:45-12:00 Selected Short Talk: Metabolic adaptations underlie epigenetic changes in chemotherapy-resistant breast cancer
Geneviève Deblois - McGill University, Canada
12:00-13:30

Lunch in the ATC Foyer

13:30-17:15

Session 3: Immunometabolism
Chair: Marcia Haigis - Harvard Medical School, USA

13:30-14:00

Metabolic and Epigenetic Reprogramming in Myeloid Cells
Mihai G. Netea - Radboud University Medical Center, The Netherlands

14:00-14:30

Regulation of antiviral and anti tumor T cell responses by sphingolipid metabolism
Guoliang Cui - German Cancer Research Center (DKFZ), Germany 

14:30-15:00

Metabolic regulation of anti tumor immunity
Susan Kaech - Salk Institute for Biological Studies, USA 

15:00-15:30

Coffee Break

15:30-16:00

Erika Pearce - Max Planck Institute of Immunobiology and Epigenetics, Germany 

16:00-16:15

Selected Short Talk: Metabolic reprogramming of myeloid cells prevents age-associated cognitive decline
Andreasson Katrin, Stanford University, USA

16:15-16:30

Selected Short Talk: Aberrant lipid metabolism and pro-inflammatory macrophage activation define
NSAID-exacerbated respiratory disease

Julia Esser-von Bieren - 
Technical University of Munich and Helmholtz Center Munich, Germany

16:30-16:45

Selected Short Talk: Calcineurin-NFAT alters the energy metabolism of activated human monocytes
Marcela Hortova Kohoutkova - International Clinical Research Center of St. Anne's University Hospital in Brno, Czech Republic 

16:45-17:00

Selected Short Talk: The mitochondrial encoded peptide MOTS-c regulates T cell metabolism to prevent autoimmune diabetes
ByungSoo Kong - Seoul National University Hospital, Republic of Korea

17:00-17:15 Flash Talk Session 1: #65, 75, 85, 135, 157, 161
17:15-19:00 Poster Session 1 (odd numbers), Helix A
19:00-21:00 Dinner in the EMBL Canteen
21:00-22:00 After Dinner drinks in the ATC Rooftop Lounge 
20:00, 21:00, 22:00 Bus departure
Day 3 - Friday 22 November 2019
TimeSpeaker
09:00-11:45 Session 4: Novel tools
Chair: Andrew Pospisilik - Van Andel Institute, USA
09:00-09:30 Fluorescent and Bioluminescent Sensor Proteins for NAD(P)
Kai Johnsson - Max Planck Institute for Medical Research, Germany 
09:30-10:00

Exploring the microbiota-host epigenetics axis in diet induced obese mice upon lifestyle intervention
Oscar Yanes - Rovira i Virgili University, Spain

10:00-10:30

Spatial metabolomics in tissues and single cells
Theodore Alexandrov - EMBL Heidelberg, Germany 

10:30-11:00

Coffee Break

11:00-11:15

Selected Short Talk: Identification of proteins on total DNA links the metabolic enzyme AHCY to chromatin
Sergi Aranda - Centre for Genomic Regulation, Barcelona Institute of Science and Technology, Spain

11:15-11:30

Selected Short Talk: Development of ZeNITH a single cells based method for metabolic profiling of human tumor
Rafael Argüello, Centre d’Immunologie de Marseille-Luminy, France

11:30-11:45 Selected Short Talk: Contextualizing chaotic cetabolic networks and their regulation
Jordan Berg - University of Utah, USA
11:45-13:30 Lunch in the ATC Foyer
13:30-17:15

Session 5: Chromatin and Metabolism
Chair: Andreas Ladurner - Ludwig Maximilian University of Munich, Germany

13:30-14:00

Epigenetic underpinnings of metabolic disease heterogeneity
John Andrew Pospisilik - Van Andel Research Institute, USA

14:00-14:30

Selected Short Talk: Model-driven rewiring of cellular metabolism and histone acetylation
Sriram Chandrasekaran - University of Michigan, USA

14:30-15:00

Hormone polyagonists as metabolic precision medicines: Discovery, mechanism and clinical validation
Matthias Tschöp - Helmholtz Zentrum München, Germany 

15:00-15:30

Coffee Break

15:30-16:00

Yeast respiratory oscillations are driven by the energetic demands of proteostasis
John O’Neill - MRC Laboratory of Molecular Biology, UK 

16:00-16:15

Selected Short Talk: Epigenetic inheritance of lipotoxic cardiomyopathy in Drosophila
Maria Clara Guida - Sanford Burnham Prebys Medical Discovery Insitute, USA

16:15-16:30

Selected Short Talk: A Creb3-Like transcription factor regulates feeding behavior through the early secretory machinery genes
Haris Khan - Ludwig Maximillians University of Munich, Germany

16:30-16:45

Selected Short Talk: The INO80 ATP-dependent chromatin remodeller promotes selective autophagy under metabolic stress conditions
Manolis Papamichos-Chronakis - Newcastle University, UK

16:45-17:00

Selected Short Talk: Uncovering metabolic pathways operating in the mammalian nucleus
Eleni Kafkia - EMBL Heidelberg. Germany

17:00-17:15

Flash Talk Session 2: # 62, 118, 138, 140, 178

17:15-19:00

Poster Session 2 (even numbers)

19:00-21:00 Conference Dinner in the EMBL Canteen
21:00-24:00 Conference Party with Live Band in the ATC Foyer
21:00, 22:00, 23:00, 0:00 Bus departure
Day 4 - Saturday 23 November 2019
TimeSpeaker
09:00-10:00

Keynote Lecture 2The Role of Metabolism in Health and Disease
Marcia Haigis - Harvard Medical School, USA 

10:00-10:30

Coffee Break

10:30-12:00

Session 6: Systems analysis of metabolism
Chair: Theodore Alexandrov - EMBL Heidelberg, Germany

10:30-11:00

Enzyme structural states as a new global readout for enzyme functional states
Paola Picotti - ETH Zurich, Switzerland 

11:00-11:30

Finding missing links in genotype-phenotype relationship using machine learning
Aleksej Zelezniak - Chalmers University of Technology, Sweden

11:30-11:45

Selected Short Talk: Large-scale protein tagging to study protein localization and dynamics of metabolic enzymes and epigenetic modifiers
Andreas Reicher - CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Austria

11:45-12:00

Selected Short Talk: Coordination of RNA abundance with cell size
Scott Berry - University of Zurich, Switzerland
12:00-12:30 Closing Remarks and Poster Prize
12:30-13:00

Packed Lunch in ATC Foyer

13:00

Departure to downtown and Frankfurt Airport